Disturbed behavior induced by high-dose antipsychotic drugs.

High-dose antipsychotic medication.

The dopamine hypothesis for the mode of action of antipsychotic drugs has been with us for some 30 years and has, by and large, withstood the test of time. It simply states that antipsychotic drugs owe their therapeutic effects to an ability to block central dopamine receptors. This has given us a working and testable explanation for the effects of these drugs and it has prompted the synthesis ...

Antipsychotic Drugs

The term psychosis refers to a variety of mental disorders characterized by one or more of the following symptoms: diminished and distorted capacity to process information and draw logical conclusions, hallucinations, delusions, incoherence or marked loosening of associations, catatonic or disorganized behavior, and aggression or violence. Antipsychotic drugs lessen these symptoms regardless of...

a survey of the tardive dyskinesia induced by antipsychotic drugs in patients with schizophrenia.

objective: tardive dyskinesia (td), is one of the important problems of the patients with schizophrenia. the emergence of these side effects depends on so many factors such as the patients' age and the duration of antipsychotic treatment. by discovering new drugs (atypical), there has been an outstanding decrease in the emergence of these side effects. the present study investigates the symptom...

Dose Equivalents for Second-Generation Antipsychotic Drugs: The Classical Mean Dose Method.

BACKGROUND The concept of dose equivalence is important for many purposes. The classical approach published by Davis in 1974 subsequently dominated textbooks for several decades. It was based on the assumption that the mean doses found in flexible-dose trials reflect the average optimum dose which can be used for the calculation of dose equivalence. We are the first to apply the method to secon...

Antipsychotic drugs and hypothermia